OSBPL5 (Oxysterol binding protein-like 5, OBPH1) shows predominant maternal expression in the
placenta but biallelic expression in fetal and newborn organs. These results suggest that the 11p15
imprinted region extends to OSBPL5. Identical results were achieved in mouse samples (Higashimoto
K, et al. 2002)
Okae H et al, (2012) found no evidence
of imprinting of OSBPL5 in the placenta and trophoblast stem cells (TS)in mouse studies. This is
concordant with Proudhon and Bourc'his, (2010) caution that maternal contamination of placental tissues may
cause apparent imprinted maternal expression.
Morcos L et al, (2011) found no evidence of
allelic expression bias in fibroblast cell lines.