Taxon:

Mouse

Gene:

Ido1

Chromosome:

08

Location:

8 A2

Description:

Ido1 (indoleamine 2,3-dioxygenase 1) showed imprinted maternal expression of both transcripts in mouse placentas (Spinelli P et al, 2019). The Ido1 promoter showed methylation in sperm and unmethylation in oocytes.
The neighbouring Ido2 gene was also imprinted.
Studies using Ido1 deficient mice showed that Ido1 alleles of paternal origin were functionally inactivated, consistent with genomic imprinting (Baban B et al, 2004).

Category:

Imprinted genes

Record:

1500

Last Modified 6/24/2019

Links:

Gene  


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