Taxon:

Mouse

Gene:

Aqp1

Chromosome:

06

Location:

6 B3; 55.3 Mb (GRCm38)

Description:

Aqp1 (aquaporin 1) showed exclusive maternal expression in the placentas of reciprocal crosses of C57BL/6J and DBA/2 mice (12 placentas were examined and all showed maternal expression - personal communication). In heterozygous knockout mice, loss of the maternal, but not the paternal allele resulted in placental and embryonic overgrowth, an increased number and branching of blood vessels, and an increase in the labyrinth area in placentae of E12.5E18.5 mice (Guo J et al, 2016). A differentially methylated region could not be detected.

Category:

Imprinted genes

Record:

1410

Last Modified 7/11/2016

Links:

Gene  


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