Taxon:

Human

Gene:

ZFAT-AS1 (provisional)

Chromosome:

08

Location:

8q24.22

Description:

ZFAT-AS1 showed monoallelic expression in at least 10 placentas investigated, and in three cases the expressed allele could be determined and was paternal. However, biallelic expression was observed in thyroid tumours (Barbaux S et al, 2012).
Metsula T et al (2014) reported monoallelic paternal expression in 3/3 informative families. However, they also reported random monoallelic expression of ZFAT itself.
Since it seems unlikely that ZFAT is imprinted then the imprinted expression of ZFAT-AS1 also seems unlikely despite the reported 6/6 cases showing paternal expression.

Category:

Imprinted genes

Record:

1349

Last Modified 3/3/2015

Links:

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