Taxon:

Human

Gene:

PWRN1

Chromosome:

15

Location:

15q11-q13 (06)

Description:

PWRN1 (prader-willi region non-protein-coding RNA 1), which is located 265 kb upstream of SNRPN, was biallelically expressed in testis and kidney, but monoallelically in 2 fetal brains. Parent-of-origin could not be determined (Buiting K et al, 2007).
Baran Y et al (2015) found evidence of imprinting of PWRN1 (using RNA-seq) in adult brain, pituitary and thyroid tissues. Allelic expression of PWRN1 in other tissues was also consistent with imprinting (adrenal gland, transverse colon, ovary, pancreas, prostate and stomach). Biallelic expression of PWRN1 was observed in testis tissue.

Category:

Imprinted genes

Record:

1261

Last Modified 8/3/2017

Links:

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