Taxon:

Mouse

Gene:

Peg10

Chromosome:

06

Location:

6 A1 (4), 1.8 cM, 47.5 Mb (GRCm38)

Description:

Peg10 (paternally expressed gene 10) is paternally expressed in the placenta, yolk sac and brain tissue from day 10 embryos, and is located next to Sgce which also shows evidence of paternal expression. Peg10 knockout mice show embryonic lethality as a result of placental defects (Ono R et al, 2006). Peg10 is a Sushi-ichi retrotransposon-derived gene with two predicted open reading frames similar to viral Gag and Pol proteins (Ono R, et al. 2001) and contains one intron. Peg10 is highly conserved amongst mammals and human PEG10 and SGCE are also paternally expressed (Ono R, et al. 2001). These genes are part of a larger cluster of genes on mouse chromosome 6 (Ono R, et al. 2003; Monk D et al, 2008).

Category:

Imprinted genes

Record:

416

Last Modified 7/10/2016

Links:

Gene  


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