Taxon:

Mouse

Gene:

Xist

Chromosome:

X

Location:

42.0 cM

Description:

There is preferential inactivation of the paternal X chromosome in extraembryonic tissues and in all cells in the early embryo (Takagi N and Sasaki M 1975; West JD et al 1977; Mak W et al 2004), resulting from preferential expression of the paternal Xist (Kay GF et al 1994).
Paternally biased X inactivation has been reported in the mouse neonatal brain (Wang X et al, 2010).
Xist function is regulated by the antisense transcript Tsix (Lee JT et al 1999).

Category:

Imprinted genes

Record:

110

Last Modified 8/3/2010

Links:

GENE  


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