Taxon:

Mouse

Gene:

Slc22a18 (Slc22a1l, Orctl2, Impt1, Itm, Tssc5, Bwscr1a)

Chromosome:

07

Location:

69.5 cM (3), Distal

Description:

Slc22a18 (solute carrier family 22 (organic cation transporter), member 18) shows strongly preferential expression of the maternal allele in various mouse tissues at fetal stages. It is expressed in tissues with metabolite transport functions, including liver, kidney, intestine, extra-embryonic membranes and placenta. Imprinted in human (Dao D et al, 1998; Cooper PR et al, 1998; Morisaki H et al, 1998).
Imprinted maternal expression of Slc22a18 was confirmed in placenta (Wang X et al, 2011 and Okae H et al, 2012 ) and in trophoblast stem cells (Okae H et al, 2012 and Golding MC et al, 2011 ).

Category:

Imprinted genes

Record:

93

Last Modified 2/4/2013

Links:

Gene  


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