Taxon:

Human

Gene:

"Autism"

Chromosome:

15

Location:

15q11-q13 (20)

Description:

Abnormalities (duplications and deletions) of chromosome 15q have been implicated in autism. In nearly all cases, the deletions or duplications have occurred on the chromosome inherited from the mother (Boyar FZ et al, 2001; Bolton PF et al, 2001; Cook EH et al. 1997; Schroer RJ et al. 1998; Repetto GM et al. 1998; Woods CG et al Am J Hum Genet 1997;61:A117; Autism Genome Project Consortium, 2007).
Transmission disequilibrium tests between autism and SNPs within ATP10A showed evidence of parent-specific transmission. Three SNPs showed maternal-specific transmission whereas one showed paternal specific transmission (Nurmi EL et al. 2003).

Category:

Parental effect

Record:

54

Last Modified 4/30/2010

Links:

OMIM   


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