Taxon:

Human

Gene:

NDN

Chromosome:

15

Location:

15q11-q13 (03)

Description:

NDN (Necdin (mouse) homologue) is paternally expressed in brain (human and mouse) and fibroblasts. It is expressed in differentiated neurones (MacDonald HR et al, 1997; Jay P et al, 1997; Watrin F et al, 1997).
Bisulfite sequencing revealed a bias towards maternal allele-specific DNA hypermethylation of the promoter CpG island of NDN, independent of tissue-specific transcriptional activity (Lau C.Y.J et al, 2004).

Category:

Imprinted genes

Record:

45

Last Modified 4/14/2014

Links:

Gene  


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