Taxon:

Human

Gene:

MKRN3 (ZNF127)

Chromosome:

15

Location:

15q11-q13 (01)

Description:

MKRN3 (Makorin3, ZNF127) is paternally expressed and putatively encodes a 505 amino acid polypeptide-containing zinc-finger motif (Jong MTC et al 1999; Glenn CC et al, 1997; Glenn CC et al, 1993; Driscoll DJ et al, 1992).
Mutations of MKRN3 are associated with precocious puberty when paternally inherited (Abreu AP et al, 2013; Simon D et al, 2016).
An antisense transcript MKRN3-AS1 (ZNF127AS, FNZ127, DN34) has been reported but its imprinting status is not yet known (Jong MTC et al, 1999): the mouse homologue Mkrn3os (Zfp127as) is reported to be paternally expressed.

Category:

Imprinted genes

Record:

44

Last Modified 3/7/2016

Links:

GENE  


*To look at further records use the Back button on your browser to return to the Summary Table

New Search

Home