MAGI2 showed monoalleic expression in embryonic
and extra-embryonic tissues of 18 d (cotyledon and brain) and
60 d (allantoid, amnios, muscle, brain, heart and intestine). The expressed allele was maternal,
which is consistent with exclusive maternal expression in mice but different from the paternal
expression of the human MAGI2 gene, as reported in the same study (Barbaux S et al, 2012).
The combination of polymorphic imprinting and opposite parents of origin in human vs mouse and cow,
raises significant doubts about the validity of the authors' claims of imprinting.