Taxon:

Human

Gene:

MAGI2

Chromosome:

07

Location:

7q21

Description:

MAGI2 was monoallelically expressed in 4 placentas and the expressed allele could be defined as paternal in 2 cases. In 3 cases, the expression was found to be biallelic ( Barbaux S et al, 2012). MAGI2 is reported to be imprinted and monoallelically expressed from maternal allele in mice and cows.
The combination of polymorphic imprinting and opposite parents of origin in human vs mouse and cow, raises significant doubts about the validity of the authors claims of imprinting.

Category:

Other

Record:

1355

Last Modified 12/29/2012

Links:

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