Taxon:

Mouse

Gene:

Cdh15

Chromosome:

08

Location:

8 E1; 8 67.0 cM

Description:

Cdh15 (cadherin-15) showed preferential paternal expression (from exons 13 and 14) in the adult preoptic area (anterior hypothalamus) (Gregg C et al, 2010).
A DMR that spans exons 10-12 of Cdh15 showed maternal-specific methylation in oocytes, 9.5 dpc embryo, quadriceps, tail and hypothalamus, but the DMR was not maintained in adult cerebral cortex, cerebellum and ES cells (Proudhon C et al, 2012). Cdh15 was showed exclusive paternal expression in the hypothalamus, and biallelic expression in quadriceps and cerebellum. In the hypothalamus expression from exon 12-13 was 10-fold higher than from exon 1, suggesting a specific imprinted transcript that arises between exons 9 and 10 (Proudhon C et al, 2012).

Category:

Imprinted genes

Record:

1329

Last Modified 1/7/2016

Links:

Gene  


*To look at further records use the Back button on your browser to return to the Summary Table

New Search

Home