Cntn3 is one of the ten genes reported by Brideau et al to be imprinted and maternally expressed in
the mouse placenta. No evidence of imprinting was detected in E17.5 brain from reciprocal crosses.
They also stated that Cntn3 is unlikely to be controlled by an ICR (Brideau
CM et al, 2010).
However, Okae H et al (2012) reported
negligible expression of Cntn3 by qPCR and whole transcriptome sequencing in E13.5 placentas. They
suggest that this gene is not imprinted. This is concordant with a caution from Proudhon and Bourc'his (2010) that maternal contamination of placental tissues may cause
apparent imprinted maternal expression.