Taxon:

Mouse

Gene:

Klrb1f (Status questioned)

Chromosome:

06

Location:

6 F3

Description:

Klrb1f (killer cell lectin-like receptor subfamily) is one of ten genes reported by Brideau et al to be imprinted and maternally expressed in the mouse placenta. No evidence of imprinting was detected in E17.5 brain from reciprocal crosses (Brideau CM et al, 2010).
However, Okae H et al (2012) reported negligible expression of Klrb1f gene name by qPCR and whole transcriptome sequencing in E13.5 placentas. They suggest that this gene is not imprinted. This is concordant with the caution from Proudhon and Bourc'his (2010) that maternal contamination of placental tissues may cause apparent imprinted maternal expression.

Category:

Other

Record:

1275

Last Modified 7/10/2016

Links:

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