Taxon:

Mouse

Gene:

Art5 (Status questioned)

Chromosome:

07

Location:

7 E3; 7 50.0 cM

Description:

Art5 (ADP-ribosyltransferase 5) is one of the ten genes reported by Brideau et al to be imprinted and maternally expressed in the mouse placenta. No evidence of imprinting was detected in E17.5 brain from reciprocal crosses (Brideau CM et al, 2010).
However, Okae H et al (2012) reported negligible expression of Art5 by qPCR and whole transcriptome sequencing in E 13.5 placentas. They suggest that this gene is not imprinted. This is concordant with the caution from Proudhon and Bourc'his, (2010) that maternal contamination of placental tissues may cause apparent imprinted maternal expression.

Category:

Other

Record:

1273

Last Modified 11/2/2015

Links:

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