Taxon:

Human

Gene:

HLA-DRB1*15 in multiple sclerosis

Chromosome:

06

Location:

6p21.3

Description:

HLA-DRB1*15 bearing MHC haplotypes increase risk of MS in people of Northern European descent. A significant over transmission of HLA-DRB1*15 from mothers was observed, suggesting that parent of origin effects at the MHC determine susceptibility to MS (Ramagopalan SV et al, 2007).

Category:

Parental effect

Record:

1159

Last Modified 11/5/2007

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