Taxon:

Mouse

Gene:

Rhox cluster

Chromosome:

X

Location:

12.7 cM

Description:

The Rhox cluster of genes (reproductive homeobox 5, Pem) was expressed predominantly from the paternally inherited X chromosome in mouse 8 cell embryos, morulas and blastocysts (note: the paternally-inherited allele is usually inactivated at this stage). In contrast, expression was predominantly from the maternally-derived allele in 7.5 dpc embryos (Kobayashi S et al, 2006).
Maclean JA et al (2011) reported maternal expression of Rhox1, Rhox4, Rhox5, Rhox6, Rhox9, Rhox10, Rhox12, Rhox13 in placenta and ES cells consistent with the expected paternal inactivation of X in these tissues.

Category:

Imprinted genes

Record:

1111

Last Modified 11/18/2011

Links:

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