Taxon:

Human

Gene:

PRIM2 (PRIM2A) (disputed)

Chromosome:

06

Location:

6p11.2

Description:

PRIM2 (PRIM2A, primase, polypeptide 2) was monoallelically expressed from the maternal allele in lymphoblast cell lines from 9 children in two CEPH pedigrees. Four other heterozygotes showed monoallelic expression (Pant PV et al, 2006). All tested individuals expressed the "A" allele.
Chung J et al. (2012) report that PRIM2 is not imprinted in placenta or blood. They present convincing evidence that the apparent imprinting was attributable to pseudogene DNA.
Morcos L et al, (2011) found no evidence of allelic expression bias in lymphoblast and fibroblast cell lines.

Category:

Other

Record:

1096

Last Modified 7/15/2012

Links:

Gene  


*To look at further records use the Back button on your browser to return to the Summary Table

New Search

Home