Taxon:

Mouse

Gene:

H13 (SPP)

Chromosome:

02

Location:

86.0 cM, Band G3

Description:

H13 (Histocompatibility 13, SPP), is imprinted and expressed exclusively from the maternal allele in newborn brain. It is preferentially maternally expressed in E13.5 embryo and placenta (Wood AJ et al, 2007).
Wood A.J et al showed the presence of alternative polyadenylation sites separated by a differentially methylated CpG island. The alternative polyadenylation sites are utilized in an allele-specific manner depending on the methylation status of the allele ( 2008).
Wang X et al, (2011) provided evidence for preferential maternal expression of H13 in E17.5 placenta.

Category:

Imprinted genes

Record:

1080

Last Modified 2/4/2013

Links:

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