Taxon:

Mouse

Gene:

Mcts2

Chromosome:

02

Location:

86.0 cM, Band G3

Description:

Mcts2 (malignant T cell amplified sequence 2) was exclusively expressed from the paternal allele in newborn brain and a strong paternal allele bias was seen at embryonic day 13.5 (Wood AJ et al, 2007). Human MCTS2 is also imprinted and paternally expressed.
MCTS2/Mtcs2 is a monoexonic retrogene derived from the X chromosome gene MCTS1/Mcts1.
The Mcts2 promoter shows germline maternal methylation.
MCTS2 retrotransposed into intron 4 of HM13/H13 of mouse and human. It is absent in the genome of cow and dog.

Category:

Imprinted genes

Record:

1077

Last Modified 9/10/2007

Links:

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