Taxon:

Mouse

Gene:

Inpp5f_v2

Chromosome:

07

Location:

73.60 cM, distal

Description:

Inpp5f_v2 (inositol polyphosphate-5-phosphatase F isoform 2) is paternally expressed in mouse brain. Inpp5f_v2 is a variant transcript whose first exon is in intron 15 of Inpp5f (Choi JD et al, 2005). The CpG island 5' of Inpp5f_v2 shows germline maternal methylation (Wood AJ et al, 2007).
Wang et al (2008) examined expression at seven SNPs in the last exon of Inpp5f. All showed preferential paternal expression in mouse neonatal brain. Based on the 3' termination of one of the Inpp5f sequences (DQ648020) the authors conclude the full length isoform of Inpp5f is also imprinted, but this claim cannot be sustained based on other sequences of this isoform in UCSC and Ensembl.

Category:

Imprinted genes

Record:

1015

Last Modified 11/9/2011

Links:

Gene  UCSC Browser  


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