Taxon:

Human

Gene:

"Clotting factor VIII"

Chromosome:

General

Location:

Description:

13 families with thrombosis and high factor VIII levels (FVIII-R) were analysed by a genome scan using 402 microsattelite markers. A single-trait-locus MOD-score analysis showed suggestive for linkage under an imprinting model at chromosomes 5 and 11. A 2-trait-locus, multiplicative model for paternal linkage of the loci on chromsomes 5 and 11 yielded a LOD score of 4.44 (Berger M et al, 2005).

Category:

Parental effect

Record:

1003

Last Modified 10/22/2011

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