Taxon:

Cow

Gene:

XIST

Chromosome:

X

Location:

82.3 MB (Bos_taurus_UMD_3.1 Primary Assembly)

Description:

Expression of XIST was analysed in chorion, allantois, liver, lung, and brain. This revealed biallelic expression from all tissues examined except chorion samples which showed preferential paternal expression. Bisulphite sequencing of an exon 1 CpG island from liver samples indicated methylation of the maternal copy only. Comparative sequence analysis suggests that the CpG-rich Xist minimal promoter and the Tsix promoter CpG island (associated with imprinted mouse Xist/Tsix transcripts) are not conserved in cattle (Dindot SV et al 2004).
Exclusive expression of MAOA from the maternal allele indicated preferential inactivation of the paternal X chromosome in bovine placentae (Xue F et al, 2002).

Category:

Imprinted genes

Record:

640

Last Modified 5/12/2013

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