Taxon:

Mouse

Gene:

Dlx5 (refuted)

Chromosome:

06

Location:

6 A1 (9a), 2.8 cM, 69 Mb (GRCm38)

Description:

Dlx5 was reported to show preferential expression from the maternal allele in frontal cortex based on restriction enzyme digested RT-PCR products from frontal cortex of reciprocal hybrids (Horike S et al, 2005). However, previously (Kimura et al, 2004) reported biallelic expression of Dlx5 in mouse brain.
Human DLX5 had been reported to be imprinted but this finding has been firmly refuted (Schule B et al, 2007). Furthermore, Schule et al. argue that the mouse imprinting data reported by Horike S et al, 2005 do not support Horike's claim that Dlx5 is imprinted. The criticism is not robust, but the data presented by Horike are insufficiently detailed to allow independent assessment.

Category:

Other

Record:

595

Last Modified 7/10/2016

Links:

Gene  


*To look at further records use the Back button on your browser to return to the Summary Table

New Search

Home