Taxon:

Human

Gene:

PON3 (paraoxonase 3)

Chromosome:

07

Location:

7q21.3 (94.83 Mb Build 36.1)

Description:

The PON genes (1-3) are closely related paralogs (65% amino acid similarity) located adjacently on chromosome 7. These proteins have been associated with coronary heart disease.
Human PON3 is biallelically expressed in placenta and fetal tissues (Monk D et al, 2008)
Mouse homologue Pon3 is preferentially maternally expressed in placenta and yolk sac samples (day 10 and 13 respectively) (Ono R, et al. 2003).

Category:

Other

Record:

414

Last Modified 4/30/2010

Links:

LocusLink   OMIM    Unigene


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