Taxon:

Mouse

Gene:

human alpha-globin promoter GFP fusion (transgene)

Chromosome:

General

Location:

Description:

A GFP fusion to the human alpha-globin promoter and enhancer elements (erythroid-specific) was used to measure parent of origin effects on transgene expression by flow cytometry. Small but significant reduction in expression following maternal transmission was observed in four of the nine lines tested. The parent of origin effect was shown to be reversible upon passage through the opposite germline (Preis JI, et al. 2003).

Category:

Parental effect

Record:

410

Last Modified 28/11/2003

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