Taxon:

Mouse

Gene:

Gatm

Chromosome:

02

Location:

69.0 cM

Description:

Gatm (L-arigine:glycine amidinotransferase) RT-PCR studies of Gatm (L-arigine:glycine amidinotransferase) showed exclusive maternal expression in the placenta and predominant maternal expression in the yolk sac, whereas biallelic expression was observed in embryonic kidney, brain and gonadal tissues. Genes located near Gatm show no evidence of imprinting and both Gatm and a neighbouring gene are associated with unmethylated CpG islands (Sandell LL et al, 2003).
However, Okae H et al, (2012) found no evidence of imprinting of Gatm in the placenta, and the apparent imprinting was attributed to high expression of this gene in maternal decidua.
Human and pig GATM are reported to be not imprinted.

Category:

Other

Record:

408

Last Modified 5/25/2015

Links:

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