Taxon:

Human

Gene:

"Acute myeloid leukaemia"

Chromosome:

07

Location:

Description:

Among 10 children with AML or related conditions, 1 case of infant monosomy 7 syndrome and two cases of biphenotypic leukaemia showed loss of maternal chromosome 7, whereas five cases with myelodysplastic syndrome and 2 cases with de novo AML showed loss of paternal alleles. These results have been used to suggest that imprinted gene(s) on chromosome 7 may be involved in MDS and AML (Katz F et al, 1992). Note the small numbers and the apparent use of "post hoc" stratification of the disease subtypes.

Category:

Other

Record:

279

Last Modified 3/15/2007

Links:


*To look at further records use the Back button on your browser to return to the Summary Table

New Search

Home