Taxon:

Human

Gene:

HLA-DQ and type 1 diabetes susceptibility

Chromosome:

06

Location:

6p21.3

Description:

At the HLA-DQ locus, in offspring with type 1 diabetes: 1) maternal alleles were different from paternal alleles and 2) maternal alleles with the DQA1*0301-DQB1*0302 haplotype showed strong transmission disequilibrium with anti-GAD-positive type 1 diabetes, while paternal alleles did not. Note: only 28 nuclear family studied (Sasaki T et al, 1999).

Category:

Parental effect

Record:

248

Last Modified 4/27/2010

Links:


*To look at further records use the Back button on your browser to return to the Summary Table

New Search

Home