Taxon:

Mouse

Gene:

Dlk1 (pref-1, Ly107, FA1, SCP1, Zog, Peg9)

Chromosome:

12

Location:

54.0 cM (1), 109.9 Mb (Feb 06)

Description:

Description: Dlk1 (delta-like homolog (Drosophila)) is paternally expressed in Peromyscus maniculatus and Mus musculus (Schmidt JV, et al. 2000;  Takada S, et al. 2000; Kobayashi S, et al. 2000). Dlk1-null mice display growth retardation, obesity, blepharophimosis and skeletal abnormalities. Moreover, these phenotypes are identical to heterozygotes who have paternally inherited but not maternally inherited alleles (Moon YS, et al. 2002). Homologues in sheep and humans also show evidence of being paternally expressed (Sheep; Human).

Category:

Imprinted genes

Record:

212

Last Modified 9/26/2007

Links:

Gene  


*To look at further records use the Back button on your browser to return to the Summary Table

New Search

Home