The gamma2 subunit of the coatomer protein complex (COPG2) is immediately adjacent to MEST and was
reported to be expressed from the paternal allele in most fetal tissues, but biallelically in fetal
brain and liver and in adult blood (Blagitko
N et al, 1999). Others found biallelic expression of COPG2 in all fetal tissues and in adult
blood lymphocytes (Yamasaki
K et al, 2000). Yamasaki et al suggest that apparent imprinting expression of COPG2 might
reflect overlapping 3' UTR transcripts from the MEST gene. In mouse Copg2 was reported to be
maternally expressed (see mouse 6).