Taxon:

Mouse

Gene:

Esx1, Spx1

Chromosome:

X

Location:

57.0 cM

Description:

As for most chromosome X genes in rodent extra-embryonic tissues, Esx1 (Extraembryonic, spermatogenesis, homeobox 1), is maternally expressed, as a result of imprinted silencing of the paternal chromosome X. Mutant mice have large placentas but are 20% smaller because of placental insufficiency (Li Y and Behringer RR, 1998).
Traditionally the 1000 or so chromosome X genes that exhibit maternal expression in extra-embryonic tissues are not counted among the imprinted genes (with the exception of Xist and Tsix).

Category:

Other

Record:

154

Last Modified 5/27/2007

Links:

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