Taxon:

Human

Gene:

CDKN1C (p57KIP2)

Chromosome:

11

Location:

11p15.5 (09)

Description:

CDKN1C (a cyclin-dependent kinase inhibitor, p57KIP2) is maternally expressed in humans and mouse. It is completely imprinted in mouse (Hatada I et al, 1995) but only partially in humans (Matsuoka S et al, 1996; Chung WY et al, 1996; Taniguchi T et al, 1997). Silencing of this transcript in persons with Beckwith-Wiedemann syndrome appears to be associated with loss of maternal methylation at the differentially methylated region KvDMR1 (Diaz-Meyer N et al, 2003).

Category:

Imprinted genes

Record:

31

Last Modified 18/07/2005

Links:

Gene  


*To look at further records use the Back button on your browser to return to the Summary Table

New Search

Home