The detailed entries of the Imprinted Gene Catalogue database were created by Benjamin Tycko, Columbia University, New York and are updated by Ian Morison


 

Detailed entry for Gene:

Zim1
ZIM2

Chromosome:

Human Chr19q13.4
Mouse Chr7 (proximal)

Imprinting:

The paternal allele of Zim1 is repressed; maternal allele active, with strong functional imprinting in several embryonic tissues; however, there is biallelic expression in neonatal and adult brain (Kim J et al, 1999). The Zim1 mRNA transcript originates close to (mouse) or overlapping with (human) Peg3.

Gene Product:

Zim1 encodes a Kruppel-type zinc finger transcription factor, which is expressed in the apical ectodermal ridges of the developing limb buds (Kim J et al, 1999).

Functional Data:

There are no functional data for Zim1.

 

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